His lab studies the molecular mechanisms that maintain mitochondrial health, with the aim of finding new treatments for inherited mitochondrial disorders and age-associated conditions linked to mitochondrial dysfunction.
His team employs state-of-the-art genome sequencing in conjunction with functional multi-omics data to investigate the impact of repetitive DNA on genome function, evolution and disease.
Her lab investigates host/microbiome interactions with a focus on host genetic effects on the gut microbiome and the role of microbial transfers between social partners.
His lab interrogates genome diversity to infer what are the forces that affect living organisms, how and when they act and how they affect biodiversity, human emotions or the differential susceptibility of different people to certain diseases.
His lab uses and develops single-cell omics methods to investigate the evolution of cell types in animals. He is co-coordinating the Biodiversity Cell Atlas (BCA) with the EBI-EMBL.
Her lab focuses on cancer as an evolutionary system. She is interested in different modes of selection active during tumorigenesis, happening in the coding or the non-coding part of the genome.
His lab uses comparative transcriptomics and functional assays in model organisms to investigate the evolution of alternative splicing and its impact in complex polygenic human diseases, such as diabetes and autism.
His lab focuses on understanding changes in genome regulation that lead to monogenic and polygenic diabetes, and on developing strategies to correct these changes in human patients.
Their lab develops machine learning methods to predict the effect of genomic variation on phenotype, with an emphasis on research that will directly impact the diagnostic yield of patient sequencing.
PRBB Building
Dr. Aiguader, 88
08003 Barcelona | Spain
https://orcid.org/0000-0001-7684-3811
